Case report
Year : 2023 Month : April Volume : 12 Issue : 2 Page : PC04 - PC06 Full Version

A Rare Case of Hodgkin’s Lymphoma Presenting as Hypereosinophilia
Arnav Tongaonkar, Archana Sonawale, Daksha Prabhat, Tejaswini Waghmare, Alhad Mulkalwar, Maurya Patel
1. Resident, Department of Medicine, Seth GSMC and KEMH, Mumbai, Maharashtra, India. 2. Professor (Additional), Department of Medicine, Seth GSMC and KEMH, Mumbai, Maharashtra, India. 3. Head, Department of Pathology, Seth GSMC and KEMH, Mumbai, Maharashtra, India. 4. Associate Professor, Department of Pathology, Seth GSMC and KEMH, Mumbai, Maharashtra, India. 5. Intern, Department of Medicine, Seth GSMC and KEMH, Mumbai, Maharashtra, India. 6. Student, Department of Medicine, Seth GSMC and KEMH, Mumbai, Maharashtra, India.
 
Correspondence Address :
Dr. Alhad Ajay Mulkalwar,
Intern, Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Acharya Donde Mard, Parel, Mumbai-400012, Maharashtra, India.
E-mail: alhad.mulkalwar@gmail.com
 
ABSTRACT
: Although eosinophilia is a recognised associated feature of Hodgkin’s Lymphoma, hypereosinophilia is seldom the presenting feature in the patient. Here, the authors report an unusual case of a 21-year-old male patient who presented to the General Medicine outpatient department of the hospital with a history of multiple episodes of left-sided pleural effusion in addition to mediastinal and cervical lymphadenopathy. Baseline investigation revealed hypereosinophilia which was persistent despite Diethylcarbamazine (DEC) and steroid therapy. Computer Tomography (CT) guided biopsy of an anterior mediastinal mass, likely to be thymus, led to the diagnosis of Hodgkin’s Lymphoma. The patient was transferred to the Haematology department where he was started on Adriamycin, Bleomycin, Vinblastine and Dacarbazine (ABVD) chemotherapy regimen. Despite the fact that blood eosinophilia is an associated finding, it is rare for a patient to present with it. The authors also discuss the discrepancies related to the credibility of eosinophilia as a prognostic marker for Hodgkin’s disease.
Keywords : Haematological malignancies, Lymphoproliferative disorders, Reed-Sternberg cells
DOI and Others : DOI: 10.7860/NJLM/2023/62745.2728 Date of Submission: Jan 08, 2023 Date of Peer Review: Jan 23, 2023 Date of Acceptance: Feb 16, 2023 Date of Publishing: Apr 01, 2023 AUTHOR DECLARATION: • Financial or Other Competing Interests: None • Was informed consent obtained from the subjects involved in the study? Yes • For any images presented appropriate consent has been obtained from the subjects. Yes PLAGIARISM CHECKING METHODS: • Plagiarism X-checker: Jan 10, 2023 • Manual Googling: Feb 24, 2023 • iThenticate Software: Feb 15, 2023 (8%) ETYMOLOGY: Author Origin
 
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