|
|
| Year:
2018 |
Month:
July
|
Volume:
7 |
Issue:
3 |
Page:
PO29 - PO33 |
Basic Haematological Scoring System-Is it the most Accurate Neonatal Sepsis Predictor?
|
| |
Correspondence
Tushar Priyanka, Hemalata,
Dr. Tushar Priyanka,
Room no -102, Hostel 11, AIIMS, Phulwarisharif, Patna-801507, Bihar, India.
E-mail: dr.tusharpriyanka@ymail.com :
|
 |
Introduction: Sepsis in neonates contributes for approximately 15% of the neonatal mortality in India. Even though a positive blood culture is pertinent for diagnosis, the technique is time consuming and is positive in only 10-40% cases.
Aim: The purpose of this study was to assess the effectiveness of haematological criteria studied by Rodwell RL et al., in 1988 in early prediction of neonatal sepsis and to correlate the score obtained with other ancillary tests like CRP, micro-ESR, Procalcitonin and culture.
Materials and Methods: In the present study, blood samples of 450 neonates with clinical suspicion of sepsis were studied for one and half years. Leishman stained peripheral smear of these neonates was evaluated and scored on a scale of 7 based on the haematological parameters of Rodwell’ s criteria. An impression of unlikely, possible and very likely of sepsis was assigned to scores of < 2, 3 or 4 and > 5 out of 7 respectively.
Results: Out of the total 450 cases, 120 (27%) cases were sepsis proven showing high Rodwell’s score and culture positivity. In these cases the performance of HSS scoring system was separately evaluated. Of the individual parameters the absolute neutrophilia count and increased immature neutrophil count had highest specificity of 91% and 92% respectively. The other parameters like, Immature: Total ratio, degenerative changes and thrombocytopenia were statistically significant with p-value <0.005.
Conclusion: Haematological scoring system is rapid, simple, inexpensive and reliable test in the early diagnosis of neonatal sepsis against the gold standard culture in differentiating infected from non-infected neonates.
|
| |
[ FULL
TEXT ] | [   ]
|
| |
Print
|
|