Case report
Year : 2026 Month : January Volume : 15 Issue : 1 Page : PC01 - PC03 Full Version

Mucinous Cystic Neoplasm of the Liver: A Case Report
BR Pallavi, M Archana, Sapna Patel, Mahesh Shetty
1. Senior Resident, Department of Patholgy, JSS Medical College, Mysore, Karnataka, India. 2. Assistant Professor, Department of Patholgy, JSS Medical College, Mysore, Karnataka, India. 3. Associate Professor, Department of Patholgy, JSS Medical College, Mysore, Karnataka, India. 4. Professor, Department of Surgical Gastroenterology, JSS Medical College, Mysore, Karnataka, India.
 
Correspondence Address :
Dr. BR Pallavi,
Senior Resident, Department of Patholgy, JSS Medical College, Mysore-570015,
Karnataka, India.
E-mail: pallubr@gmail.com
 
ABSTRACT
: Mucinous Cystic Neoplasms (MCNs) of the hepatobiliary tract constitute <5% of all hepatic cysts. Present case report is of MCN of the liver with radiological dilemma and special emphasis on histopathology combined with immunohistochemistry. The present case is a 36-year-old female who presented with pain in the upper abdomen for five months. The pain was insidious in onset, mild in intensity, dull aching, and non radiating. There was a history of intermittent loose stools. Routine laboratory investigations such as complete blood count, liver function tests, and renal function tests were within normal limits. Viral markers including Human Immunodeficiency Virus (HIV), Hepatitis B Surface antigen (HbsAg), and anti-HCV were negative. Ultrasound abdomen showed a well-defined cystic lesion measuring 6.5×4.8 cm in the left lobe of the liver (segment II/III) with thin internal echoes. A radiological diagnosis of hydatid cyst was made. Laparoscopic deroofing of the cyst with drainage was performed, and the specimen was sent for histopathological examination. Grossly, the specimen consisted of grey-brown tissue fragments measuring 6.5×3 cm. On microscopic examination, the cyst was lined by cuboidal to columnar epithelium with mucinous cytoplasm and basally oriented nuclei. The subepithelium showed ovarian-like stroma. A diagnosis of benign MCN was made on histopathology. Immunohistochemistry using Oestrogen Receptor (ER) showed strong nuclear positivity in the stromal cells, confirming the diagnosis. The postoperative period was uneventful, and the patient improved symptomatically.
Keywords : Cystic lesions, Mucin secreting tumours, Ovary like stroma
DOI and Others : DOI: 10.7860/NJLM/2026/82629.2949 Date of Submission: Aug 15, 2025 Date of Peer Review: Sep 23, 2025 Date of Acceptance: Oct 23, 2025 Date of Publishing: Jan 01, 2026 AUTHOR DECLARATION: • Financial or Other Competing Interests: None • Was informed consent obtained from the subjects involved in the study? Yes • For any images presented appropriate consent has been obtained from the subjects. Yes PLAGIARISM CHECKING METHODS: • Plagiarism X-checker: Sep 08, 2025 • Manual Googling: Oct 15, 2025 • iThenticate Software: Oct 22, 2025 (15%) ETYMOLOGY: Author Origin EMENDATIONS: 6
 
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