Case report
Year : 2025 Month : January-March Volume : 14 Issue : 1 Page : PC01 - PC02

A Case Report of Primary Peritoneal Mesothelioma in a Male Patient
Sarbashis Hota, Rajarshi Aich, Srabani Chakrabarti
1. Senior Resident, Department of Pathology, CNCI, New Town Campus, Kolkata, West Bangal, India. 2. Senior Resident, Department of Pathology, CNCI, New Town Campus, Kolkata, West Bangal, India. 3. Senior Consultant, Department of Pathology, CNCI, New Town Campus, Kolkata, West Bangal, India.
 
Correspondence Address :
Sarbashis Hota,
House No-840/10, Raghunathpur, Jhargram-721507, Kolkata, West Bangal, India.
E-mail: sarbashishota94@gmail.com
 
ABSTRACT
Mesothelioma is a malignant neoplasm arising from the mesothelial lining of serous cavities. Commonly arising from the pleura, this rare malignancy is strongly associated with asbestos exposure; however, origins from other sites, such as the tunica vaginalis of the testis, have also been reported in the literature. Hereby, the authors present a case of primary peritoneal mesothelioma in a 39-year-old male patient. The patient, a worker in the marble polishing industry, presented with metabolically active extensive mesenteric, peritoneal, and omental thickening involving the entire abdominal cavity, along with intra-abdominal lymphadenopathy, which was initially diagnosed as metastatic papillary adenocarcinoma based on an omental biopsy. No other metabolically active focus was detected on Positron Emmision Tomography (PET)-Computed Tomography (CT) elsewhere in the body. A review of the histopathology sections showed omental fatty tissue infiltrated by a neoplasm arranged predominantly in a papillary architecture, composed of cells showing a tendency toward dyscohesion. The neoplastic cells were round-oval, without overt nuclear pleomorphism, possessing small round nuclei with a single prominent nucleolus and a moderate amount of eosinophilic cytoplasm. Mitotic activity was inconspicuous. The tumour expressed Calretinin and WT1, leading to a final diagnosis of mesothelioma. Despite active management with intraperitoneal chemotherapy, the patient expired after three months.
Keywords : Eastern India, Neoplasm, Primary peritoneal malignancy
 
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