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Original article / research
Year: 2026 Month: January Volume: 15 Issue: 1 Page: PC01 - PC03

Mucinous Cystic Neoplasm of the Liver: A Case Report

 
Correspondence BR Pallavi, M Archana, Sapna Patel, Mahesh Shetty,
Dr. BR Pallavi,
Senior Resident, Department of Patholgy, JSS Medical College, Mysore-570015,
Karnataka, India.
E-mail: pallubr@gmail.com
:
Mucinous Cystic Neoplasms (MCNs) of the hepatobiliary tract constitute <5% of all hepatic cysts. Present case report is of MCN of the liver with radiological dilemma and special emphasis on histopathology combined with immunohistochemistry. The present case is a 36-year-old female who presented with pain in the upper abdomen for five months. The pain was insidious in onset, mild in intensity, dull aching, and non radiating. There was a history of intermittent loose stools. Routine laboratory investigations such as complete blood count, liver function tests, and renal function tests were within normal limits. Viral markers including Human Immunodeficiency Virus (HIV), Hepatitis B Surface antigen (HbsAg), and anti-HCV were negative. Ultrasound abdomen showed a well-defined cystic lesion measuring 6.5×4.8 cm in the left lobe of the liver (segment II/III) with thin internal echoes. A radiological diagnosis of hydatid cyst was made. Laparoscopic deroofing of the cyst with drainage was performed, and the specimen was sent for histopathological examination. Grossly, the specimen consisted of grey-brown tissue fragments measuring 6.5×3 cm. On microscopic examination, the cyst was lined by cuboidal to columnar epithelium with mucinous cytoplasm and basally oriented nuclei. The subepithelium showed ovarian-like stroma. A diagnosis of benign MCN was made on histopathology. Immunohistochemistry using Oestrogen Receptor (ER) showed strong nuclear positivity in the stromal cells, confirming the diagnosis. The postoperative period was uneventful, and the patient improved symptomatically.
 
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