Case report
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A Case Report of Primary Peritoneal Mesothelioma in a Male Patient |
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| Correspondence
Address : Sarbashis Hota, House No-840/10, Raghunathpur, Jhargram-721507, Kolkata, West Bangal, India. E-mail: sarbashishota94@gmail.com |
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| Mesothelioma is a malignant neoplasm arising from the mesothelial lining of serous cavities. Commonly arising from the pleura, this rare malignancy is strongly associated with asbestos exposure; however, origins from other sites, such as the tunica vaginalis of the testis, have also been reported in the literature. Hereby, the authors present a case of primary peritoneal mesothelioma in a 39-year-old male patient. The patient, a worker in the marble polishing industry, presented with metabolically active extensive mesenteric, peritoneal, and omental thickening involving the entire abdominal cavity, along with intra-abdominal lymphadenopathy, which was initially diagnosed as metastatic papillary adenocarcinoma based on an omental biopsy. No other metabolically active focus was detected on Positron Emmision Tomography (PET)-Computed Tomography (CT) elsewhere in the body. A review of the histopathology sections showed omental fatty tissue infiltrated by a neoplasm arranged predominantly in a papillary architecture, composed of cells showing a tendency toward dyscohesion. The neoplastic cells were round-oval, without overt nuclear pleomorphism, possessing small round nuclei with a single prominent nucleolus and a moderate amount of eosinophilic cytoplasm. Mitotic activity was inconspicuous. The tumour expressed Calretinin and WT1, leading to a final diagnosis of mesothelioma. Despite active management with intraperitoneal chemotherapy, the patient expired after three months. | ||||||
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