Original article / research
Study of Clinico-Pathological Spectrum of Meningioma with WHO Grading
Poornima V Kamatar,
#S1, Gallery Aparment, 1st Cross 1st Stage, Shirur Park, Vidyanagar, Hubballi-580021, Karnataka, India.
Introduction: Meningiomas are the most frequent non glial primary Central Nervous System (CNS) tumour. Several histopathological patterns of meningiomas are classified and graded. A standard classification system aims at providing a tool for estimating the recurrence and overall survival of meningioma patients.
Aim: The aim was to study clinical, radiological and pathological presentation of Meningioma and to grade meningiomas according to 2016 WHO classification in a tertiary care centre.
Materials and Methods: It is an observational study of 51 cases of meningioma conducted in the department of Pathology, SDM college of Medical sciences and Hospital, Dharwad from June 2011 to June 2021. The demographic details, clinical features, radiological findings, histopathological findings and grading of meningioma according to 2016 WHO classification were analysed.
Results: A total of 51 meningioma cases were studied in which age ranged between 16 and 79 years. Among 51 cases, 33 (64.70 %) were females and 18 (35.29 %) were males. The most common symptom was headache seen in 39 patients (76.47%) followed by vomiting in 11 patients (21.56%). Radiologically, commonest lobe involved was frontal lobe in 22 cases (43.13%). The most common histological subtype was meningothelial meningioma in 18 (35.29%) cases followed by psammomatous meningioma in 13 (25.49%), transitional meningioma in 12 (23.52%), fibroblastic meningioma in 4 (7.84%), atypical meningioma in 2 (3.92%), secretory meningioma 1 (1.96%) and microcystic meningioma in 1 (1.96%) case. A total of 49 (96.07%) cases of meningiomas were of Grade-I & 2 (3.92 %) were of Grade-II with none in Grade-III.
Conclusion: Meningiomas occur more commonly in females than in males with multiple clinical presentation. Histopathological examination helps to type the meningioma and grade them accordingly.
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