Original article / research
Histopathological Analysis of Sinonasal and Nasopharyngeal Lesions- A Retrospective Study
Aditya Nagar 2nd Line, Reddypalem Road, Guntur, Andhra Pradesh, India.
Introduction: Sinonasal and nasopharyngeal lesions is a common problem in the present environment with diagnostic and therapeutic dilemma. Majority of the lesions present clinically as polypoid masses. Histopathological examination of these lesions is essential for the definitive diagnosis because management and prognosis vary among different lesions.
Aim: To determine the incidence of various nasal lesions reported in a rural tertiary care hospital, and to compare these lesions in relation to demographic data of the patients.
Materials and Methods: This retrospective study was conducted on the specimens received at histopathology section from the ENT department of a tertiary care hospital from April 2018 to November 2021. The specimens were fixed in 10% formalin, processed and then stained with haematoxylin and eosin. Required data were obtained from the histopathology records.
Results: The present study was conducted on a total of 100 cases. Amongst these, 61 were males and 39 were females. An overall male predominance was noted. Maximum numbers of cases were diagnosed in the age group 31-40 years. Non neoplastic constituted N=86 cases (86%), neoplastic benign lesions constituting N=10 cases (10%) and malignant masses constituted N=04 cases (04%) of the total lesions in the present study. Inflammatory polyps were the most commonly diagnosed cases and few fungal rhinosinusitis in postCOVID-19 patients were noted in the present study. Inverted papillomas were predominant benign neoplastic lesions whereas nasopharyngeal carcinomas were noted as predominant malignant lesions.
Conclusion: Most of the sinonasal and nasopharyngeal lesions reported were non neoplastic and inflammatory polyp being most common. Malignant lesions were reported in advanced age of life.
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