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Original article / research
Year : 2022 Month : January-March Volume : 11 Issue : 1 Page : PO12 - PO14

Neutrophil Lymphocyte Ratio and Serum Ferritin Levels in COVID-19: A Cross-sectional Study

 
Correspondence Address :
Dr. Shashi Upreti,
Associate Professor, Department of Pathology, Government Doon Medical College,
Dehradun, Uttarakhand, India.
E-mail: shaship27@gmail.com
Introduction: Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) causing Coronavirus Disease (COVID-19) has challenged the world. A complete blood workup as well as continuous tracking of haematological parameters play a vital role in revealing the risks of disease progression and eventually help in better treatment and outcome.

Aim: To access the haematological parameters {Complete Blood Count (CBC), Neutrophil Lymphocyte Ratio (NLR) and Serum Ferritin (S. ferritin) levels} in COVID-19 patients to correlate its association with the severity of the disease.

Materials and Methods: The present study was a cross-sectional study in which 200 patients who were confirmed as COVID-19 positive by real time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) in the month of July-August 2020 were included. Blood was collected from patients of COVID-19 using the routine methods and was evaluated for CBC and S. ferritin levels. Neutrophil Lymphocyte Ratio (NLR) was also calculated.

Results: The NLR was positively correlated with severity of COVID-19. Patients with higher NLR levels were admitted to Intensive Care Unit (ICU) because of severity in their condition. In the present study, 42 of 47 (89.4%) ICU patients had S. ferritin levels >1000 ng/mL whereas only 8 (5.2%) of non ICU patients had S. ferritin levels >1000 ng/mL.

Conclusion: The NLR and S. ferritin positively correlated with the severity of COVID-19 disease.
 
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