Original article / research
Mucoepidermoid Carcinoma of the Head and Neck: Clinico-Pathologic Study of 12 Cases
Dr. Ranjan Agrawal,
Professor, Department of Pathology, Rohilkhand Medical College Hospital, Pilibhit Bypass Road, Bareilly, India.
Introduction: Mucoepidermoid carcinoma (MEC), one of the most common salivary gland malignancies, but it is rare in children. MEC occurs mainly in the parotid gland, followed by the minor salivary glands. Palate being the second common site.
Aim: The present study was undertaken with the aim of studying the clinico-pathological presentations as well as the histopathological grading of head and neck mucoepidermoid carcinoma.
Materials and Methods: During the 2 year retro-prospective study a total of 12 cases diagnosed as Mucoepidermoid carcinoma in the head and neck region in a tertiary care hospital were included in the present study. Clinic-pathological presentations of these patients were recorded. Histological grading was done as per the Armed Forces Institute of Pathology criteria.
Results: Out of the 12 cases, 8 were males and 4 females with the age ranging from 18 to 65 years; the average age being 40.08 years. Four patients each presented with ulcer and ill-defined swelling and 2 each, as growth and cyst. Histopathologically 5 patients were low grade, 6 as intermediate grade and 1 as high grade.
Conclusion: Prognosis of patients with MEC greatly depends on the tumour stage as well as the histologic grade of the lesion. Typical treatment involves surgical excision for low grade lesions and surgical excision with elective neck dissection in the ipsilateral neck followed by adjuvant radiation therapy for higher grade lesions. Grade II tumours are treated similarly to grade III since, even though the behaviour resembles grade I tumours, they possess a predilection for nodal metastasis as in grade III lesions.
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