N J L M

 
Subscribe Via RSS
  • Home
  • About
    Salient Features Bibliographic Information Abstracting and Indexing Specialties Covered Publisher Journal Policy
  • Issues
    Current Issue Online Ahead of Print Archive Forthcoming issue
  • Editorial
    Editorial Statements Editorial-PeerReview Process Editorial Board Publication Ethics & Malpractice Join us
  • Authors
    Submit an Article Manuscript Instructions Manuscript Assistance Publication Charges Paid Services Early Online Publication Service
  • Reviewers
    Apply as Reviewer Reviewers Acknowledgment
  • Search
    Simple Search Advanced Search
  • Member
    Register Login
  • Contact
  • Subscription
Original article / research
Year: 2013 Month: December Volume: 2 Issue: 4 Page: 12 - 17

Clinico – Hematological Analysis of Pancytopenia: A Bone Marrow Study

 
Correspondence Anita P. Javalgi, Vijay D. Dombale,
Dr. Anita P. Javalgi,
Assistant Professor, Department of Pathology,
Bldeu’s Shri B M Patil Medical College,
Sholapur Road Bijapur.
Email: javalgianita@gmail.com
Ph: 09739619068
:
Background: Pancytopenia is characterized by anemia, leucopenia and thrombocytopenia, a common hematological problem. It is a striking feature of many serious and life threatening illnesses. The disease pattern varies in different population groups, in age pattern, nutritional status and prevalence of infective disorder. Present study was conducted to assess the etiology, clinical profile and bone marrow morphology of pancytopenia. Objective: To know various patterns of clinical presentation and co-relate hematological parameters and bone marrow study with clinical findings, in differentiating causes of pancytopenia.

Methods: A two-years study from January 2009 to December 2010 was conducted in Department of Pathology. Total 106 pancytopenia patients aged 15-65 years were studied to determine their clinical features, peripheral smear study and bone marrow morphology. The etiological pattern was assessed through relevant investigations done on the respective patients.

Results: Bone marrow study showed 68.8% hypercellular marrow, 15% normocellular and 16.2 % hypocellular marrow. Males(57.5%) were affected more than females(42.5%) and the commonest cause for pancytopenia was megaloblastic anemia (73.5%), followed by iron deficiency anemia (12.2%), malaria(3.7%), leukemia (2.8%), SLE (1.8%), aplastic anemia (1.8%), multiple myeloma (0.9%), myelofibrosis(0.9%), MDS(0.9%) and hyperspleenism (0.9%).

Conclusion: Large number of patients had reversible etiology. Hence complete work up including clinical details with hematological examination along with bone marrow study will lead to early and proper diagnosis of case followed by proper treatment.
 
[ FULL TEXT ]   |   [ ]
 
Print
  • Article Utilities

    • Readers Comments (0)
    • Article in PDF
    • Citation Manager
    • Article Statistics
    • Link to PUBMED
    • Print this Article
    • Send to a Friend
    • Go To Issues

      • Current Issue
      • Past Issues
  • Search Articles

    • Simple Search
    • Advance Search
  • Authors Facilities

    • Extensive Author Support
    • Submit Manuscript
    • ONLINE First Facility
    • NJLM Pre Publishing
  • Quick Links

    • REVIEWER
    • ACCESS STATISTICS
  • Users

    • Register
    • Log in
  • Pages

    • About
    • Issues
    • Editorials
    • Authors
    • Reviewers
    • Search
    • Contacts
  • Issues Archives

  • Affiliated Websites

    • JCDR Prepublishing
    • Neonatal Database Home
    • JCDR Neonatal Database download center