Original article / research
Lipid Profile Patterns in a Rural Area of Ramanagara District
Dr. Y Sahana,
Department of Biochemistry, Dr Chandramma Dayananda Sagar Institue of Medical Education and Research, Harohalli, Kanakapura Taluk, Ramanagara District, Karnataka, India.
Introduction: Dyslipidemia is one of the risk factors contributing to atherosclerosis leading to Cardiovascular Disease (CVD), which in-turn is a major contributor to the mortality and morbidity globally.
Aim: To examine the burden of lipid profile pattern in a rural area.
Materials and Methods: The present study was a cross-sectional study done in the rural area of Harohalli, Ramanagara district, Karnataka, India. A total of 560 patients who came for routine blood check-up were enrolled for the study. The study population was further divided into subgroups as <20 years, 21-40 years, 41-60 years, >60 years. Percentage analysis and association of lipid profile parameters and age as well as gender was established using appropriate statistical methods like percentage analysis, Chi-square test, Venn-diagram and trend chart.
Results: Less than half of the population were found to have high serum levels of Triglyceride (TG), Low Density Lipoprotein (LDL) and TG/HDL ratio. High-Density Lipoprotein cholesterol (HDL-c) was found to be significantly associated with gender (p value <0.01). HDL-c was found to increase progressively after 50 years of age in females compared to males of same age. Also, an increasing trend of TG/HDL-c ratio was noted in both genders with a marked elevation being noted in post-menopausal females.
Conclusion: Abnormal lipid profile was noted even in young population of the study group; thus, an early screening and follow-up in both males and females is required keeping in view their future progression to CVDs.
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