Homozygous HbD Punjab- A Case Report of Family Study
Dr. Reema Bhushan,
1113, Sector-4 RK Puram, New Delhi-110022, Delhi, India.
|Homozygous HbD Punjab is a rarely reported haemoglobin variant. It co-elutes with other haemoglobin variants on alkaline and acid electrophoresis. However, on Cation Exchange-High Performance Liquid Chromatography (CE-HPLC), it elutes in the specific D-Window. Hence this is a sensitive method to clearly identify this haemoglobin variant. Here, a family study is presented in which both parents were HbD Punjab heterozygous and both children were HbD Punjab homozygous. All of them were clinically asymptomatic and were unaware of their status. This case is reported because of its rarity and clinical significance particularly if it occurs with other haemoglobin variants.|
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