Hepcidin- A Burgeoning Biomarker
Dr. Hemkant Manikrao Deshmukh,
Assistant Professor, Department of Biochemistry,
Terna Medical College and Hospitals, Sector-12 Nerul,
Navi Mumbai-400706, Maharashtra, India.
|The discovery of hepcidin has triggered a virtual ignition of studies on iron metabolism and related disorders. The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli. Several human diseases are associated with variations in hepcidin concentrations. The evaluation of hepcidin in biological fluids is therefore a promising device in the diagnosis and management of medical situations in which iron metabolism is affected. Thus, it made us to recapitulate role of hepcidin as biomarker.|
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